Innate Immune Defense Through RNA Interference

@article{Fritz2006InnateID,
  title={Innate Immune Defense Through RNA Interference},
  author={Jörg H. Fritz and Stephen E. Girardin and Dana J. Philpott},
  journal={Science's STKE},
  year={2006},
  volume={2006},
  pages={pe27 - pe27}
}
RNA interference (RNAi, also known as RNA silencing) has recently emerged as a fundamental and widespread regulator of gene expression. New developments in this field implicate RNAi in the innate immune response to infection in plants and animals. Evidence from plants, tissue culture cells, and Caenorhabditis elegans–based systems previously suggested that RNAi plays a role in the defense against viral infection, but definitive evidence using viruses and whole animals has been lacking. Two… Expand
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