Inmunohistochemical Expression of PCNA , p 53 and bcl-2 in Pleomorphic Adenomas

@inproceedings{GordnNez2009InmunohistochemicalEO,
  title={Inmunohistochemical Expression of PCNA , p 53 and bcl-2 in Pleomorphic Adenomas},
  author={Manuel-Antonio Gord{\'o}n-N{\'u}{\~n}ez and Gustavo Pina Godoy and Rosilene Calazans Soares and L{\'e}lia B Souza},
  year={2009}
}
The aim of the study was to determine the immunohistochemical expression of the PCNA, p53 and bcl-2 proteins in pleomorphic adenomas. Nineteen specimens of pleomorphic adenomas were selected for analysis by the streptavidin-biotin-peroxidase method with antibodies against p53, PCNA and bcl-2 proteins. It was observed weak labeling for p53 in 12 cases (63.1%) and for PCNA in 8 (42.1%). With respect to the bcl-2 labeling index, no expression of this protein was detected in 12 cases, corresponding… CONTINUE READING

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