Inland-coastal bifurcation of southern East Asians revealed by Hmong-Mien genomic history

  title={Inland-coastal bifurcation of southern East Asians revealed by Hmong-Mien genomic history},
  author={Zi-Yang Xia and Shi Yan and Chuan-Chao Wang and Hongxiang Zheng and Fan Zhang and Yuchi Liu and Ge Yu and Bin-Xia Yu and Li-Li Shu and Li Jin},
The early history of the Hmong-Mien language family and its speakers is elusive. A good variety of Hmong-Mien-speaking groups distribute in Central China. Here, we report 903 high-resolution Y-chromosomal, 624 full-sequencing mitochondrial, and 415 autosomal samples from 20 populations in Central China, mainly Húnán Province. We identify an autosomal component which is commonly seen in all the Hmong-Mien-speaking populations, with nearly unmixed composition in Pahng. In contrast, Hmong and Mien… Expand
Cultural variation impacts paternal and maternal genetic lineages of the Hmong-Mien and Sino-Tibetan groups from Thailand
The Hmong-Mien and Sino-Tibetan speaking groups are known as hill tribes in Thailand and the results attest to the impact of cultural practices on patterns of mtDNA vs. MSY variation. Expand
Cultural variation impacts paternal and maternal genetic lineages of the Hmong-Mien and Sino-Tibetan groups from Thailand
The results attest to the impact of cultural practices on patterns of mtDNA vs. MSY variation and a striking difference between Hmong and IuMien (Mien-speaking) groups. Expand
Reconstructing the Human Genetic History of Mainland Southeast Asia: Insights from Genome-Wide Data from Thailand and Laos
The first detailed insights into the genetic profiles of Thai/Lao ethnolinguistic groups are provided, which should be helpful for reconstructing human genetic history in MSEA and selecting populations for participation in ongoing whole genome sequence and biomedical studies. Expand
Fine-Scale Genetic Structure and Natural Selection Signatures of Southwestern Hans Inferred From Patterns of Genome-Wide Allele, Haplotype, and Haplogroup Lineages
  • Mengge Wang, Didi Yuan, +8 authors Guanglin He
  • Medicine
  • Frontiers in Genetics
  • 2021
A case and ideal strategy is provided to reconstruct the detailed demographic evolutionary history of Guizhou Hans, which provided new insights into the fine-scale genomic formation of one ethnolinguistically specific targeted population from the comprehensive perspectives of the shared unlinked alleles, linked haplotypes, and paternal and maternal lineages. Expand
Phylogenetic analysis of the Y-chromosome haplogroup C2b-F1067, a dominant paternal lineage in Eastern Eurasia
It is suggested that ancient populations with varied C2b-F1067 sublineages played an important role during the formation of most modern populations in Eastern Eurasia, and thus eventually became the founding paternal lineages of these populations. Expand
Extensive ethnolinguistic diversity in Vietnam reflects multiple sources of genetic diversity
It is found that the Vietnamese ethnolinguistic groups harbor multiple sources of genetic diversity that are associated with heterogeneous ancestry sharing profiles in each language family, and linguistic diversity does not completely match genetic diversity. Expand
Graph Embedding Method Based Genetical Trajectory Reveals Migration History Among East Asians
The graph and structure learning based Graph Embedding method commonly used in single cell mRNA sequencing was applied to human population genetics research to decrease the data dimension and the human population trajectory of East Asia was reconstructed to discover the inseparable relationship between the Chinese population and other East Asian populations. Expand


Genetic structure of Hmong-Mien speaking populations in East Asia as revealed by mtDNA lineages.
  • Bo Wen, H. Li, +15 authors L. Jin
  • Biology, Medicine
  • Molecular biology and evolution
  • 2005
The results indicate that the Hmong populations had experienced more contact with the northern East Asians, a finding consistent with historical evidence. Expand
Human Migration through Bottlenecks from Southeast Asia into East Asia during Last Glacial Maximum Revealed by Y Chromosomes
Molecular anthropological studies of the populations in and around East Asia have resulted in the discovery that most of the Y-chromosome lineages of East Asians came from Southeast Asia. However,Expand
An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs
An updated phylogeny of the O2a-M95 lineage is characterized, which improves the resolution of this lineage, and allows for greater tracing of the prehistory of human populations in eastern Asia and the Pacific, which may yield novel insights into the patterns of language diversification and population movement in these regions. Expand
Ancient genomes document multiple waves of migration in Southeast Asian prehistory
Ancient migrations in Southeast Asia The past movements and peopling of Southeast Asia have been poorly represented in ancient DNA studies (see the Perspective by Bellwood). Lipson et al. generatedExpand
The prehistoric peopling of Southeast Asia
Neither interpretation fits the complexity of Southeast Asian history: Both Hòabìnhian hunter-gatherers and East Asian farmers contributed to current Southeast Asian diversity, with further migrations affecting island SEA and Vietnam. Expand
Y Chromosomes of 40% Chinese Descend from Three Neolithic Super-Grandfathers
It is found that all the Paleolithic divergences were binary; however, three strong star-like Neolithic expansions at ∼6 kya (thousand years ago) indicates that ∼40% of modern Chinese are patrilineal descendants of only three super-grandfathers at that time, suggesting that the main patrilinesal expansion in China occurred in the Neolithic Era and might be related to the development of agriculture. Expand
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans
The findings reveal that western Eurasian genetic signatures in modern-day Native Americans derive not only from post-Columbian admixture, as commonly thought, but also from a mixed ancestry of the First Americans. Expand
Reconstructing Austronesian population history in Island Southeast Asia
It is shown that all sampled Austronesian groups harbour ancestry that is more closely related to aboriginal Taiwanese than to any present-day mainland population, suggesting that either there was once a substantial Austro-Asiatic presence in Island Southeast Asia, orAustronesian speakers migrated to and through the mainland, admixing there before continuing to western Indonesia. Expand
137 ancient human genomes from across the Eurasian steppes
The genomes of 137 ancient and 502 modern human genomes illuminate the population history of the Eurasian steppes after the Bronze Age and document the replacement of Indo-European speakers of West Eurasian ancestry by Turkic-speaking groups of East Asian ancestry. Expand
Reconstructing Native American Population History
It is shown that the initial peopling followed a southward expansion facilitated by the coast, with sequential population splits and little gene flow after divergence, especially in South America. Expand