Injured corneal epithelial cells promote myodifferentiation of corneal fibroblasts.

@article{Nakamura2002InjuredCE,
  title={Injured corneal epithelial cells promote myodifferentiation of corneal fibroblasts.},
  author={Kunihiko Nakamura and Daijiro Kurosaka and Mami Yoshino and Takeshi Oshima and Hiroyo Kurosaka},
  journal={Investigative ophthalmology & visual science},
  year={2002},
  volume={43 8},
  pages={2603-8}
}
PURPOSE To determine whether injured corneal epithelial cells stimulate myodifferentiation in corneal fibroblasts and whether transforming growth factor (TGF)-beta is involved. METHODS Rabbit corneal fibroblasts were cultured on collagen gel, with or without cocultured corneal epithelial cells or with partially scraped epithelial cells, on a companion plate separated by a permeable membrane. To evaluate fibroblast-induced gel contraction, gel thickness was measured daily relative to the… CONTINUE READING