Injection site effects on the pharmacokinetics and glucodynamics of insulin lispro and regular insulin.

@article{Braak1996InjectionSE,
  title={Injection site effects on the pharmacokinetics and glucodynamics of insulin lispro and regular insulin.},
  author={Edith Ter Braak and James R. Woodworth and Rossella Bianchi and Benito J. Cerimele and D. Willem Erkelens and Joseph Helenus Hubert Thijssen and David L. Kurtz},
  journal={Diabetes care},
  year={1996},
  volume={19 12},
  pages={
          1437-40
        }
}
OBJECTIVE The pharmacokinetics and glucodynamics of a new insulin analog, insulin lispro, and regular human insulin were compared and contrasted after subcutaneous administrations in femoral, deltoid, and abdominal injection sites. RESEARCH DESIGN AND METHODS Single 0.2 U/kg doses of insulin lispro and regular insulin were administered to 12 healthy subjects in a six-way randomized crossover fashion. Each dose was given after an overnight fast in one of three injection sites: abdominal… CONTINUE READING
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