Injection of microfilariae induces resistance to Brugia malayi infection in ferrets and accelerates development of lymphostatic disease.

Abstract

Ferrets injected intravenously with living microfilariae or cutaneously with microfilariae followed by intravenous injection developed partial resistance to a challenge infection as measured by recovery of adult filariae from lymphatics. Following a challenge infection, the ferrets injected with microfilariae developed lymphatic pathology characteristic of… (More)

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