Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis.

Stefano Pluchino, Angelo Quattrini, +11 authors Gianvito Martino
Published 2003 in Nature

Abstract

Widespread demyelination and axonal loss are the pathological hallmarks of multiple sclerosis. The multifocal nature of this chronic inflammatory disease of the central nervous system complicates cellular therapy and puts emphasis on both the donor cell origin and the route of cell transplantation. We established syngenic adult neural stem cell cultures and… (More)

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References

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Showing 1-10 of 32 references

Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons.

M Laura Feltri, Diana Graus Porta, +9 authors Lawrence Wrabetz
The Journal of cell biology
2002

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

Jong-Hoon Kim, Jonathan M Auerbach, +8 authors Ron McKay
Nature
2002

Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system.

Rossella Galli, Roberta Fiocco, +7 authors Angelo L Vescovi
Development
2002

Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation.

J S Alexander, John W Elrod
Journal of anatomy
2002

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.

Yang D Teng, Erin B Lavik, +5 authors Evan Y Snyder
Proceedings of the National Academy of Sciences…
2002

New concepts in the immunopathogenesis of multiple sclerosis

Bernhard Hemmer, Juan J. Archelos, Hans-Peter Hartung
Nature Reviews Neuroscience
2002

Treatment of neural injury with marrow stromal cells.

Michael Chopp, Yi Li
The Lancet. Neurology
2002

Why does remyelination fail in multiple sclerosis?

Robin J. M. Franklin
Nature Reviews Neuroscience
2002

Linker, R. A. et al. CNTF is a major protective factor in demyelinating CNS disease
Nature Med. 8, 620–624
2002

Differentiation potential of adult stem cells.

D Clarke, J Frisén
Current opinion in genetics & development
2001

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis.

Abstract

Topics

6 Figures and Tables

Cited By

Time-dependent fate of transplanted neural precursor cells in experimental autoimmune encephalomyelitis mice.

Induced Stem Cells as a Novel Multiple Sclerosis Therapy.

Neural stem/progenitor cells as promising candidates for regenerative therapy of the central nervous system

The remyelination Philosopher's Stone: stem and progenitor cell therapies for multiple sclerosis

Grafting neural precursor cells promotes functional recovery in an SCA1 mouse model.

Human stem cells for CNS repair

LINGO-1-Fc-Transduced Neural Stem Cells Are Effective Therapy for Chronic Stage Experimental Autoimmune Encephalomyelitis

Intranasal delivery of stem cells as therapy for central nervous system disease.

Stem Cells and Cancer Stem Cells, Volume 13

Overexpression of CD44 in Neural Precursor Cells Improves Trans- Endothelial Migration and Facilitates Their Invasion of Perivascular Tissues In Vivo

References

Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons.

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system.

Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation.

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.

New concepts in the immunopathogenesis of multiple sclerosis

Treatment of neural injury with marrow stromal cells.

Why does remyelination fail in multiple sclerosis?

a neurotrophic cytokine as modulator in neuroinflammation

Differentiation potential of adult stem cells.

Blog articles referencing this paper

Slides referencing similar topics

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis.

Abstract

Topics

6 Figures and Tables

Cited By

Time-dependent fate of transplanted neural precursor cells in experimental autoimmune encephalomyelitis mice.

Induced Stem Cells as a Novel Multiple Sclerosis Therapy.

Neural stem/progenitor cells as promising candidates for regenerative therapy of the central nervous system

The remyelination Philosopher's Stone: stem and progenitor cell therapies for multiple sclerosis

Grafting neural precursor cells promotes functional recovery in an SCA1 mouse model.

Human stem cells for CNS repair

LINGO-1-Fc-Transduced Neural Stem Cells Are Effective Therapy for Chronic Stage Experimental Autoimmune Encephalomyelitis

Intranasal delivery of stem cells as therapy for central nervous system disease.

Stem Cells and Cancer Stem Cells, Volume 13

Overexpression of CD44 in Neural Precursor Cells Improves Trans- Endothelial Migration and Facilitates Their Invasion of Perivascular Tissues In Vivo

References

Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons.

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system.

Extracellular matrix, junctional integrity and matrix metalloproteinase interactions in endothelial permeability regulation.

Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells.

New concepts in the immunopathogenesis of multiple sclerosis

Treatment of neural injury with marrow stromal cells.

Why does remyelination fail in multiple sclerosis?

a neurotrophic cytokine as modulator in neuroinflammation

Differentiation potential of adult stem cells.

Similar Papers

Blog articles referencing this paper

Slides referencing similar topics