Injection of Wild Type Embryonic Stem Cells into Mst1 Transgenic Blastocysts Prevents Adult-Onset Cardiomyopathy

Abstract

Embryonic stem cells have the capacity to differentiate into a wide range of cell types. We previously described that blastocyst injection of wild type (WT) embryonic stem cells (ESCs) into various knockout (KO) mouse models of human disease prevents disease from occurring. In this study we ask if the blastocyst approach can also correct defects in a mouse… (More)
DOI: 10.1007/s12015-010-9206-6

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