Injection-molding versus extrusion as manufacturing technique for the preparation of biodegradable implants.

@article{RothenWeinhold1999InjectionmoldingVE,
  title={Injection-molding versus extrusion as manufacturing technique for the preparation of biodegradable implants.},
  author={Alexandra Rothen-Weinhold and Kamel Besseghir and Evelyne Vuaridel and E Sublet and Nathalie Oudry and Frank Kubel and Robert Gurny},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={1999},
  volume={48 2},
  pages={113-21}
}
Polylactic acid (PLA) is a biocompatible and biodegradable material with wide utility for many applications, including the design of controlled-release systems for pharmaceutical agents. The factors determining the degradation kinetics of these systems include the composition and the molecular mass of the polymer, the morphology and the structure of the device, and the influence of thermal processes. The processing of the polymer determines the structure and design of the device, and influences… CONTINUE READING

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