Injectable intrathecal delivery system for localized administration of EGF and FGF-2 to the injured rat spinal cord.


The administration of growth factors (GFs) for treatment of experimental spinal cord injury (SCI) has shown limited benefits. One reason may be the mode of delivery to the injury site. We have developed a minimally invasive and safe drug delivery system (DDS) consisting of a highly concentrated collagen solution that can be injected intrathecally at the… (More)


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