Injectable collagenase clostridium histolyticum for Dupuytren's contracture.

@article{Hurst2009InjectableCC,
  title={Injectable collagenase clostridium histolyticum for Dupuytren's contracture.},
  author={L. Hurst and M. Badalamente and V. Hentz and R. Hotchkiss and F. Kaplan and R. Meals and Theodore M Smith and J. Rodzvilla},
  journal={The New England journal of medicine},
  year={2009},
  volume={361 10},
  pages={
          968-79
        }
}
BACKGROUND Dupuytren's disease limits hand function, diminishes the quality of life, and may ultimately disable the hand. Surgery followed by hand therapy is standard treatment, but it is associated with serious potential complications. Injection of collagenase clostridium histolyticum, an office-based, nonsurgical option, may reduce joint contractures caused by Dupuytren's disease. METHODS We enrolled 308 patients with joint contractures of 20 degrees or more in this prospective, randomized… Expand
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Paper Mentions

Interventional Clinical Trial
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Dupuytren's disease results in deformity of the hand and this can lead to trouble with daily activities. Treatment traditionally involves cutting out diseased tissue, however this can… Expand
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Multiple concurrent collagenase clostridium histolyticum injections to dupuytren’s cords: an exploratory study
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