Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes.

@article{Azoulay2014InitiationOW,
  title={Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes.},
  author={Laurent Azoulay and Sophie Dell'aniello and Teresa A. Simon and Christel Renoux and Samy Suissa},
  journal={European heart journal},
  year={2014},
  volume={35 28},
  pages={
          1881-7
        }
}
AIMS An increased risk of stroke was observed in two atrial fibrillation (AF) trials of oral factor Xa inhibitors, when patients were transitioned to open label warfarin at the end of the study. The objective of this study is to determine whether initiation of warfarin is associated with an increased risk of stroke in patients with AF. METHODS AND RESULTS Using the UK Clinical Practice Research Datalink, a nested case-control analysis was conducted within a cohort of 70 766 patients with AF… CONTINUE READING

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