Initiation of mRNA decay in bacteria

  title={Initiation of mRNA decay in bacteria},
  author={Soumaya Laalami and L{\'e}na Zig and Harald Putzer},
  booktitle={Cellular and Molecular Life Sciences},
The instability of messenger RNA is fundamental to the control of gene expression. In bacteria, mRNA degradation generally follows an “all-or-none” pattern. This implies that if control is to be efficient, it must occur at the initiating (and presumably rate-limiting) step of the degradation process. Studies of E. coli and B. subtilis, species separated by 3 billion years of evolution, have revealed the principal and very disparate enzymes involved in this process in the two organisms. The… CONTINUE READING

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