Initiation of hepatitis C virus infection requires the dynamic microtubule network: role of the viral nucleocapsid protein.


Early events leading to the establishment of hepatitis C virus (HCV) infection are not completely understood. We show that intact and dynamic microtubules play a key role in the initiation of productive HCV infection. Microtubules were required for virus entry into cells, as evidenced using virus pseudotypes presenting HCV envelope proteins on their surface… (More)
DOI: 10.1074/jbc.M807873200


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