Initiation of hemodialysis treatment leads to improvement of T-cell activation in patients with end-stage renal disease.

@article{Kaul2000InitiationOH,
  title={Initiation of hemodialysis treatment leads to improvement of T-cell activation in patients with end-stage renal disease.},
  author={Harald Kaul and Matthias Girndt and Urban Sester and Martina Sester and Hans K{\"o}hler},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2000},
  volume={35 4},
  pages={611-6}
}
Patients with chronic renal failure show an immunodeficiency characterized by frequent infectious complications and a low response to vaccinations. This is paralleled in vitro by a low T-cell proliferation on mitogenic stimuli because of an impaired costimulation by accessory cells. Furthermore, alterations of the cytokine profile are correlated with impaired immune function. The immune system is influenced by both uremia and renal replacement therapy. To evaluate the influence of hemodialysis… CONTINUE READING

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