Initiation of distension-induced descending peristaltic reflex in opossum esophagus: role of muscle contractility.

@article{Muinuddin2001InitiationOD,
  title={Initiation of distension-induced descending peristaltic reflex in opossum esophagus: role of muscle contractility.},
  author={Ahmad Muinuddin and W G Paterson},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2001},
  volume={280 3},
  pages={G431-8}
}
The balloon distension (BD)-induced descending peristaltic reflex in the opossum smooth muscle esophagus is abolished in vitro when a Ca(2+)-free Krebs solution is placed at the site of distension, suggesting that either synaptic transmission occurs at the origin of the reflex or initiation of the reflex requires the development of muscle tension in response to BD. To test the latter possibility, an 8- to 10-cm length of smooth muscle esophagus was placed in a dual-chamber organ bath, isolating… CONTINUE READING