Initiation of RPS2-Specified Disease Resistance in Arabidopsis Is Coupled to the AvrRpt2-Directed Elimination of RIN4

@article{Axtell2003InitiationOR,
  title={Initiation of RPS2-Specified Disease Resistance in Arabidopsis Is Coupled to the AvrRpt2-Directed Elimination of RIN4},
  author={Michael J. Axtell and Brian J. Staskawicz},
  journal={Cell},
  year={2003},
  volume={112},
  pages={369-377}
}

Figures from this paper

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The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation.
TLDR
It is demonstrated that AvrRpt2-dependent cleavage of RIN4 at RCS2 is functionally critical in vivo, and at least two bacterial virulence factors target the same domain of R IN4, a approximately 30-aa plant-specific signature sequence found in a small Arabidopsis protein family that may be additional targets for these bacterial virulent factors.
Molecular Basis for the RIN 4 Negative Regulation of RPS 2 Disease Resistance
TLDR
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