Initiation and maintenance of in vitro decidualization are independent of hormonal sensitization in vivo.

@article{Mani1992InitiationAM,
  title={Initiation and maintenance of in vitro decidualization are independent of hormonal sensitization in vivo.},
  author={Shaila K. Mani and Joanne Julian and S A Lampelo and Stanley R. Glasser},
  journal={Biology of reproduction},
  year={1992},
  volume={47 5},
  pages={785-99}
}
The effects of in vivo hormonal sensitization on the competence of uterine stromal (US) cells to decidualize in vitro were assessed. In vitro differentiation of uterine stroma isolated from Day 4 pregnant rats, sensitized to respond to a decidual stimulus, was compared to that in nonsensitized immature, castrated or cycling rats. The initiation of in vitro decidualization--as monitored by the expression of the decidual markers desmin and laminin in rat US cells--was independent of the hormonal… CONTINUE READING