Initial serotonin transport into viable platelets and imipramine binding to platelet membranes

  title={Initial serotonin transport into viable platelets and imipramine binding to platelet membranes},
  author={Marie Luise Rao and Christine Frahnert and O. Zagorski},
  journal={Journal of Neural Transmission},
Summary. Transport of serotonin into human platelets is a paradigm for neuronal reuptake to investigate putatively low neurotransmitter availability in certain psychiatric diseases. However, inconsistent results have been obtained on serotonin binding to platelet membranes at equilibrium and transport during initial phase into isolated platelets. In the present study we applied a rapid oil-centrifugation technique to study 14C-serotonin transport for 15 s into viable human platelets during the… 

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Regulation of Serotonin Transport in Human Platelets by Tyrosine Kinase Syk

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