Initial sequencing and analysis of the human genome

@article{Lander2001InitialSA,
  title={Initial sequencing and analysis of the human genome},
  author={Eric S. Lander and Lauren Linton and Bruce Birren and Chad Nusbaum and Michael C. Zody and Jennifer DeLuca Baldwin and Keri Devon and Ken Dewar and Miss Doyle and W. FitzHugh and Rainer Funke and Diane Gage and Kelley Harris and Andrew C Heaford and Jane Howland and Lisa M Kann and Jessica Lehoczky and Rosie Levine and Paul J McEwan and Kevin Mckernan and Jim Meldrim and Jill P. Mesirov and Carla M F C Miranda and William L. Morris and J. Naylor and Mihaela Rosetti and Ralph Santos and Andrew Sheridan and Carrie L. Sougnez and Y Stange-Thomann and Nikola Stojanovic and Anuradha Subramanian and Dudley Wyman and John Rogers and J. Sulston and Rachel Ainscough and Stephan Beck and David B Bentley and John A Burton and Christopher M Clee and N. P. Carter and Alan Coulson and Rebecca Deadman and Panagiotis Deloukas and Andrew Dunham and Ian Dunham and Richard Durbin and L. W. French and Darren Grafham and Simon R Gregory and Tim Hubbard and Sean J. Humphray and Adrienne Hunt and Matthew H. Jones and Christine Lloyd and Amanda A. McMurray and Lucy Matthews and Stephen Mercer and S. Milne and James C. Mullikin and Andrew J. Mungall and Robert Plumb and Michael Ross and Ratna Shownkeen and S. Sims and Robert H. Waterston and Richard K. Wilson and LaDeana W. Hillier and John D. McPherson and Marco A. Marra and Elaine R. Mardis and Lucinda A. Fulton and Asif T. Chinwalla and Kymberlie H. Pepin and Warren Gish and Stephanie L. Chissoe and Michael C. Wendl and Kimberly D. Delehaunty and Tracie L. Miner and Andrew Delehaunty and James B. Kramer and Lisa L. Cook and Robert S. Fulton and Darryll Johnson and Patrick Minx and Sandra W. Clifton and Trevor Hawkins and Elbert Branscomb and Paul F Predki and Paul Richardson and S Wenning and Tom Slezak and Norman Doggett and J. F. Cheng and Anne Raaby Olsen and Susan Lucas and Chris Elkin and Ed Uberbacher and Marvin Frazier and Richard A. Gibbs and Donna M. Muzny and Steven E. Scherer and John B. Bouck and Erica Sodergren and K. C. Worley and Catharine M Rives and J H Gorrell and M. L. Metzker and S. L. Naylor and Raju S. Kucherlapati and David L. G. Nelson and George Weinstock and Yoshiyuki Sakaki and Asao Fujiyama and Masahira Hattori and Tetsushi Yada and Atsushi Toyoda and Takehiko Itoh and Chikara Kawagoe and Hidemi Watanabe and Yasushi Totoki and Tim Taylor and Jean Weissenbach and R. Heilig and W. Saurin and François Artiguenave and Philippe Brottier and Thomas Bruls and Eric Pelletier and Catherine Robert and Patrick Wincker and Douglas R. Smith and Lynn Doucette-Stamm and Marc J Rubenfield and Keith Weinstock and Hye Min Lee and J W Dubois and Andr{\'e} Rosenthal and Matthias Platzer and Gerald J Nyakatura and Stefan Taudien and Andreas Rump and Huanming Yang and Jun Yu and Jing Wang and Gregory T. Huang and Jun Gu and Leroy Hood and Lee Rowen and Anuradha Madan and Shizhen Qin and Ronald W. Davis and Nancy A. Federspiel and A. Pia Abola and Michael J. Proctor and Richard M. Myers and Jeremy Schmutz and Mark Dickson and David R. Cox and Maynard V. Olson and Rajinder Kaul and Christopher Raymond and Nobuyoshi Shimizu and Kazuhiko Kawasaki and Shinsei Minoshima and G. A. Evans and M. A. Athanasiou and Ryan Schultz and B. A. Roe and Feng Chen and Huaqin Pan and Juliane Ramser and Hans Lehrach and Richard Reinhardt and W. Richard McCombie and Melissa de la Bastide and Neilay Dedhia and Helmut Bl{\"o}cker and Klaus Hornischer and Gabriele Nordsiek and Richa Agarwala and L. Aravind and Jeffrey A. Bailey and Alex Bateman and Serafim Batzoglou and Ewan Birney and Peer Bork and Daniel G. Brown and Christopher B. Burge and Lorenzo Cerutti and Han Cai Chen and Deanna M. Church and Michele Clamp and R. R. Copley and Tobias Doerks and Sean R. Eddy and Evan E. Eichler and Terrence S. Furey and James E. Galagan and James G. R. Gilbert and Cynthia Harmon and Yoshihide Hayashizaki and David Haussler and Henning Hermjakob and Karsten Hokamp and Wonhee Jang and L. Steven Johnson and Thomas A. Jones and Simon Kasif and A Kaspryzk and Scott W. Kennedy and W. James Kent and Paul Kitts and Eugene V. Koonin and Ian Korf and David Kulp and Doron Lancet and Todd M. Lowe and Aoife McLysaght and T. G. Mikkelsen and John V Moran and Nanno H. Mulder and Victor J. Pollara and Chris Paul Ponting and Greg D. Schuler and Joerg Schultz and Guy Slater and Arian FA Smit and Elia Stupka and Danielle Thierry-Mieg and Jean Thierry-Mieg and Lukas Wagner and J. Wallis and Raymond Wheeler and Audra L Williams and Yuri I. Wolf and Kenneth H. Wolfe and Samuel P Yang and Rufang Yeh and Francis Collins and M. Susan Guyer and Jane Peterson and Adam L. Felsenfeld and Kris A. Wetterstrand and Ari Patrinos and M. J. Morgan and Pieter A de Jong and Joseph J. Catanese and Kazutoyo Osoegawa and Hiroaki Shizuya and Sungchun Choi and Y. J. Chen and J Szustakowki},
  journal={Nature},
  year={2001},
  volume={409},
  pages={860-921}
}
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence. 
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References

Publications referenced by this paper.
Showing 1-10 of 428 references

KuÈnstliche Kreuzung bei Pisum sativum

von Tschermack, E. Uber
Berichte der Deutsche Botanische Gesellschaft • 1900
View 7 Excerpts
Highly Influenced

Sur la loie de disjonction des hybrides

H. De Vries
Comptes Rendue Hebdemodaires, Acad. Sci. Paris 130, • 1900
View 7 Excerpts
Highly Influenced

Random-clone strategy for genomic restriction mapping in yeast.

Proceedings of the National Academy of Sciences of the United States of America • 1986
View 5 Excerpts
Highly Influenced

Toward a physical map of the genome of the nematode Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America • 1986
View 4 Excerpts
Highly Influenced

Complete nucleotide sequence of SV40 DNA

W Fiers
Nature 273, • 1978
View 4 Excerpts
Highly Influenced

The nucleotide sequence of bacteriophage FX174

F Sanger
J Mol Biol 125, • 1978
View 4 Excerpts
Highly Influenced

Nucleotide sequence of bacteriophage F X174 DNA

F Sanger
Nature 265, • 1977
View 6 Excerpts
Highly Influenced