Initial response to protease-inhibitor-based antiretroviral therapy among children less than 2 years of age in South Africa: effect of cotreatment for tuberculosis.

@article{Reitz2010InitialRT,
  title={Initial response to protease-inhibitor-based antiretroviral therapy among children less than 2 years of age in South Africa: effect of cotreatment for tuberculosis.},
  author={Cordula Reitz and Ashraf H. Coovadia and Stephen C. Ko and Tammy Meyers and Renate Strehlau and Gayle Sherman and Louise Kuhn and Elaine J. Abrams},
  journal={The Journal of infectious diseases},
  year={2010},
  volume={201 8},
  pages={1121-31}
}
BACKGROUND South African guidelines recommend protease-inhibitor-based antiretroviral therapy (ART) with lopinavir-ritonavir for human immunodeficiency virus (HIV)-infected children <36 months of age. We investigated factors associated with viral suppression and mortality among young children initiating ART. METHODS Treatment-naive, ART-eligible, HIV-infected children (aged 6-104 weeks) were enrolled in an ART strategies trial in South Africa and initiated protease-inhibitor-based ART… CONTINUE READING

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