Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma.

@article{Schuster2007InitialEW,
  title={Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma.},
  author={David M. Schuster and John R. Votaw and Peter T. Nieh and Weiping Yu and Jonathon A. Nye and Viraj A. Master and F. DuBois Bowman and Muta M. Issa and Mark M. Goodman},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2007},
  volume={48 1},
  pages={56-63}
}
UNLABELLED Conventional imaging techniques have serious limitations in the detection, staging, and restaging of prostate carcinoma. Anti-1-amino-3-(18)F-fluorocyclobutane-1-carboxylic acid (anti-(18)F-FACBC)is a synthetic l-leucine analog that has excellent in vitro uptake within the DU-145 prostate carcinoma cell line and orthotopically implanted prostate tumor in nude rats. There is little renal excretion compared with (18)F-FDG. The present study examines anti-(18)F-FACBC uptake in patients… CONTINUE READING