Initial events in exercise-induced muscular injury.

  title={Initial events in exercise-induced muscular injury.},
  author={Robert B Armstrong},
  journal={Medicine and science in sports and exercise},
  volume={22 4},
Immediately following unaccustomed exercise, particularly that with eccentric contractions, there is evidence of injury to skeletal muscle fibers: a) disruption of the normal myofilament structures in some sarcomeres, observable with both light and electron microscope and b) loss of intramuscular proteins (e.g., creatine kinase enzymes) into the plasma, indicating damage to sarcolemma. This pathology is probably responsible for the temporary reductions in muscle force and delayed-onset soreness… CONTINUE READING
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