Initial binding and recellularization of decellularized mouse lung scaffolds with bone marrow-derived mesenchymal stromal cells.

@article{Daly2012InitialBA,
  title={Initial binding and recellularization of decellularized mouse lung scaffolds with bone marrow-derived mesenchymal stromal cells.},
  author={Amanda B. Daly and John M Wallis and Zachary D. Borg and Ryan W Bonvillain and Bin Deng and Bryan A. Ballif and Diane M. Jaworski and Gilman B Allen and Daniel Weiss},
  journal={Tissue engineering. Part A},
  year={2012},
  volume={18 1-2},
  pages={1-16}
}
Recellularization of whole decellularized lung scaffolds provides a novel approach for generating functional lung tissue ex vivo for subsequent clinical transplantation. To explore the potential utility of stem and progenitor cells in this model, we investigated recellularization of decellularized whole mouse lungs after intratracheal inoculation of bone marrow-derived mesenchymal stromal cells (MSCs). The decellularized lungs maintained structural features of native lungs, including intact… CONTINUE READING

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