Initial North American experience with botulinum toxin type A for treatment of anismus.

@article{Joo1996InitialNA,
  title={Initial North American experience with botulinum toxin type A for treatment of anismus.},
  author={Ji Seon Joo and Feran Agachan and Bruce G. Wolff and Juan J. Nogueras and Steven D. Wexner},
  journal={Diseases of the colon and rectum},
  year={1996},
  volume={39 10},
  pages={1107-11}
}
PURPOSE Botulinum toxin type A (BTX-A), produced by Clostridium botulinum, is a potent neurotoxin. The purpose of this study was to evaluate the efficacy of BTX-A for treatment of anismus. MATERIALS AND METHODS All patients treated with BTX-A for anismus were evaluated. Eligibility criteria included a history of chronic assisted evacuation (laxatives, enemas, or suppositories), demonstration of anismus by cinedefecogram and electromyography, and failure of a minimum of three sessions of… CONTINUE READING
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