Initial, clinical trial of a new, specific 5-HT reuptake inhibitor, citalopram (Lu 10-171).

@article{Gottlieb1980InitialCT,
  title={Initial, clinical trial of a new, specific 5-HT reuptake inhibitor, citalopram (Lu 10-171).},
  author={Philip Gottlieb and T Wandall and K. Fredericson Over\o},
  journal={Acta psychiatrica Scandinavica},
  year={1980},
  volume={62 3},
  pages={236-44}
}
Ten endogenously depressed inpatients were treated once daily for at least 4 weeks with 40-50 mg citalopram (Lu 10-171) - a specific serotonin reuptake inhibitor. The Hamilton rating scale for depression and global assessment indicated pronounced or moderate response in seven patients and slight or no response in three. Side effects were few, mild and transient and neither anticholinergic nor cardiotoxic effects were observed. No difference was observed between responders and non-responders as… CONTINUE READING

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