Inhibitory responses to exogenous adenosine in murine proximal and distal colon.

@article{Zizzo2006InhibitoryRT,
  title={Inhibitory responses to exogenous adenosine in murine proximal and distal colon.},
  author={Maria Grazia Zizzo and Flavia Mul{\`e} and Rosa Serio},
  journal={British journal of pharmacology},
  year={2006},
  volume={148 7},
  pages={956-63}
}
The aims of the present study were firstly, to characterize pharmacologically the subtypes of P(1) purinoreceptors involved in the inhibitory effects induced by exogenous adenosine in longitudinal smooth muscle of mouse colon, and secondly, to examine differences in the function and distribution of these receptors between proximal and distal colon. Adenosine (100 microM-3 mM) caused a concentration-dependent reduction of the amplitude of spontaneous contractions in the proximal colon, and… CONTINUE READING
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