Inhibitory neurotransmission in rat spinal cord: co-localization of glycine- and GABAA-receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining.

@article{Bohlhalter1994InhibitoryNI,
  title={Inhibitory neurotransmission in rat spinal cord: co-localization of glycine- and GABAA-receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining.},
  author={Stephan Bohlhalter and Hanns Mohler and Jean Marc Fritschy},
  journal={Brain research},
  year={1994},
  volume={642 1-2},
  pages={59-69}
}
Synaptic inhibition in rat spinal cord is mediated by the amino acids gamma-aminobutyric acid (GABA) and glycine. Most spinal cord neurons respond to both neurotransmitters, suggesting co-expression of GABAA- and strychnine-sensitive glycine-receptors in individual cells. While the distribution of glycine-receptors has been extensively characterized, much less is known about the cellular localization of GABAA-receptors in spinal cord neurons. In the present study, the distribution of GABAA… CONTINUE READING

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