Inhibitory mechanisms of resveratrol in platelet activation: pivotal roles of p38 MAPK and NO/cyclic GMP.

Abstract

Resveratrol has been reported to have antiplatelet activity; however, the detailed mechanisms have not yet been resolved. This study aimed to systematically examine the detailed mechanisms of resveratrol in the prevention of platelet activation in vitro and in vivo. Resveratrol (0.05-0.25 micromol/l) showed stronger inhibition of platelet aggregation… (More)

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@article{Shen2007InhibitoryMO, title={Inhibitory mechanisms of resveratrol in platelet activation: pivotal roles of p38 MAPK and NO/cyclic GMP.}, author={Ming Y. Shen and George Hsiao and Chang L. Liu and Tsorng H Fong and Kuang Hao Lin and Duen S Chou and Joen-Rong Sheu}, journal={British journal of haematology}, year={2007}, volume={139 3}, pages={475-85} }