Inhibitory mechanisms of antibiotics targeting elongation factor Tu.

@article{Hogg2002InhibitoryMO,
  title={Inhibitory mechanisms of antibiotics targeting elongation factor Tu.},
  author={Tanis Hogg and Jeroen R. Mesters and Rolf Hilgenfeld},
  journal={Current protein & peptide science},
  year={2002},
  volume={3 1},
  pages={
          121-31
        }
}
Since the pioneering discovery of the inhibitory effects of kirromycin on bacterial elongation factor Tu (EF-Tu) more than 25 years ago [1], a great wealth of biological data has accumulated concerning protein biosynthesis inhibitors specific for EF-Tu. With the subsequent discovery of over two dozen naturally occurring EF-Tu inhibitors belonging to four different subclasses, EF-Tu has blossomed into an appealing antimicrobial target for rational drug discovery efforts. Very recently… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
12 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…