Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages.

Abstract

It has not been resolved whether macrophages or airway epithelial cells primarily respond to infectious and inflammatory stimuli and initiate a cell-to-cell inflammatory interaction within the airways. We hypothesized that the airway epithelial cells are primary responders that activate macrophages in response to environmental stimuli. To investigate the… (More)

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