Inhibitory influence of mecamylamine on ethanol withdrawal-induced symptoms in C57BL/6J mice

@article{Bhutada2010InhibitoryIO,
  title={Inhibitory influence of mecamylamine on ethanol withdrawal-induced symptoms in C57BL/6J mice},
  author={Pravinkumar S. Bhutada and Yogita R. Mundhada and Kuldeep U Bansod and Sudhir N. Umathe and Vivek P. Kahale and Pankaj V. Dixit and Dharmendra R. Mundhada},
  journal={Behavioural Pharmacology},
  year={2010},
  volume={21},
  pages={90-95}
}
Several reports show the involvement of neuronal nicotinic acetylcholine receptors (nAChRs) in the behavioral effects of ethanol, including ethanol drinking and relapse. Therefore, this study evaluated the effects of mecamylamine, a nAChR antagonist, on ethanol withdrawal signs. Ethanol dependence was induced in C57BL/6J mice by ethanol liquid diet administration. Animals were provided with nutritionally balanced control liquid diet (600 kcal/l) as their sole nutrient source on day 0; from days… 
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