Inhibitory effects of sweet cherry anthocyanins on the obesity development in C57BL/6 mice.

@article{Wu2014InhibitoryEO,
  title={Inhibitory effects of sweet cherry anthocyanins on the obesity development in C57BL/6 mice.},
  author={Tao Wu and Qiong Tang and Zhuoping Yu and Zichun Gao and Hao Hu and Wei Chen and Xiaodong Zheng and Ting Yu},
  journal={International journal of food sciences and nutrition},
  year={2014},
  volume={65 3},
  pages={351-9}
}
In the present study, purified sweet cherry anthocyanins (CACN) were evaluated to determine their inhibitory effects on adipocyte differentiation of 3T3-L1 cells and their anti-obesity properties in male C57BL/6 mice fed with high-fat diet (HFD). CACN prevented HFD-induced obesity in C57BL/6 mice. In vivo experiment revealed that 40 and 200 mg/kg of CACN in food reduced the body weight by 5.2% and 11.2%, respectively. CACN supplementation could also reduce the size of adipocytes, leptin… CONTINUE READING
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