Inhibitory effects of quercetin on angiogenesis in larval zebrafish and human umbilical vein endothelial cells.

@article{Zhao2014InhibitoryEO,
  title={Inhibitory effects of quercetin on angiogenesis in larval zebrafish and human umbilical vein endothelial cells.},
  author={Daxian Zhao and Chuanjie Qin and Xiaohui Fan and Yuncong C Li and Binhe Gu},
  journal={European journal of pharmacology},
  year={2014},
  volume={723},
  pages={360-7}
}
Angiogenesis plays an essential role in many physiological and pathological processes. Quercetin, a plant pigment and traditional Chinese medicinal herb, is an important flavonoid that has anti-cancer activity. However, the function of quercetin in blood vessel development in vivo and in vitro is still unclear. In this study, we investigated the anti-angiogenic activity of quercetin in zebrafish embryos and in human umbilical vein endothelial cells (HUVECs). Our results showed that quercetin… CONTINUE READING