Inhibitory effects of prostaglandin E1 on activation of hepatic stellate cells in rabbits with schistosomiasis.

@article{Zou2007InhibitoryEO,
  title={Inhibitory effects of prostaglandin E1 on activation of hepatic stellate cells in rabbits with schistosomiasis.},
  author={Wei-long Zou and Zhen Yang and Yun-jin Zang and Dong-jian Li and Zhi-peng Liang and Zhong-yang Shen},
  journal={Hepatobiliary & pancreatic diseases international : HBPD INT},
  year={2007},
  volume={6 2},
  pages={176-81}
}
BACKGROUND Liver fibrosis is the result of an imbalance between synthesis and degradation of extracellular matrix proteins of the liver. At the cellular and molecular levels, this progressive process is mainly characterized by activation of hepatic stellate cells (HSCs). Schistosoma japonica is one of the most prevalent causes of liver fibrosis in China. It is characterized by hepatocyte damage, inflammation, and chronic parasite egg-induced granuloma formation leading to fibrosis. This study… CONTINUE READING
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