Corpus ID: 23642077

Inhibitory effects of 2-[(diethylamino)acetyl]-1,2,3,4-tetrahydro-6, 7-dimethoxyl-1-[1'-(6"-methoxy-2"-naphthalenyl)ethyl]-isoquinoline on isolated guinea pig papillary muscle and heart atrium.

@article{Wu1995InhibitoryEO,
  title={Inhibitory effects of 2-[(diethylamino)acetyl]-1,2,3,4-tetrahydro-6, 7-dimethoxyl-1-[1'-(6"-methoxy-2"-naphthalenyl)ethyl]-isoquinoline on isolated guinea pig papillary muscle and heart atrium.},
  author={G. T. Wu and H. Dong and Z. J. Liang},
  journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  year={1995},
  volume={16 3},
  pages={
          239-42
        }
}
AIM To investigate the cardiac actions of 2-[(diethylamino)acetyl]-1,2,3,4-tetrahydro-6, 7-dimethoxyl-1-[1'-(6"-methoxy-2"-naphthalenyl) ethyl]-isoquinoline (CPU57) by comparison with nifedipine and focus on its mechanism of actions. METHOD The following were measured and recorded: 1) the rate and contraction of spontaneous beating of the guinea pigs right heart atrium, 2) the isometric tension of the electrically stimulated left heart atrium and the right papillary muscles. RESULTS CPU57… Expand