Inhibitory effects of histamine on interleukin 2 and gamma interferon production of different human T helper cell subsets.

Abstract

We have previously demonstrated that histamine can inhibit human helper T cells by direct interaction with these cells. It has now been investigated whether histamine inhibits lymphokine production by various subsets of CD4+ human T cells separated with the Leu-8 (p80) and Leu-18 (anti-CD45R;p220) monoclonal antibodies (MoAb). Histamine was shown to… (More)

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@article{Dohlsten1988InhibitoryEO, title={Inhibitory effects of histamine on interleukin 2 and gamma interferon production of different human T helper cell subsets.}, author={Mikael Dohlsten and G Persdotter Hedlund and Helen Sj{\"o}gren and R Carlsson}, journal={Scandinavian journal of immunology}, year={1988}, volume={28 6}, pages={727-33} }