Inhibitory effects of formoterol on platelet-activating factor induced eosinophil chemotaxis and degranulation.

@article{Eda1993InhibitoryEO,
  title={Inhibitory effects of formoterol on platelet-activating factor induced eosinophil chemotaxis and degranulation.},
  author={Ryousuke Eda and Hisashi Sugiyama and Russell J. Hopp and Chiharu M. Okada and Againdra K. Bewtra and Robert G. Townley},
  journal={International archives of allergy and immunology},
  year={1993},
  volume={102 4},
  pages={
          391-8
        }
}
A new long-acting beta 2-agonist, formoterol, has been reported to have a greater efficacy and duration of action in asthmatic patients as compared to conventional beta 2-agonists. We recently demonstrated that formoterol inhibited antigen-induced late asthmatic response (LAR) and accompanying airway eosinophilia in guinea pigs. In this study, we investigated the direct effect of formoterol in vitro on human eosinophil function, focusing on platelet-activating factor (PAF)-induced eosinophil… CONTINUE READING
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