Inhibitory effects of fatty acid monoesters of 2-O-beta-D-glucosylglycerol on Epstein-Barr virus activation.

@article{Colombo1998InhibitoryEO,
  title={Inhibitory effects of fatty acid monoesters of 2-O-beta-D-glucosylglycerol on Epstein-Barr virus activation.},
  author={Diego Colombo and Antonio Scala and I M Taino and Lucio Toma and Fiamma Ronchetti and Harukuni Tokuda and Hoyoku Nishino and Akito Nagatsu and Jinsaku Sakakibara},
  journal={Cancer letters},
  year={1998},
  volume={123 1},
  pages={83-6}
}
In a screening for cancer chemopreventing agents several glycosylglycerols were found to be active. In order to optimize the anti-tumor activity of this class of compounds, a series of 1-O-acyl-2-O-beta-D-glucopyranosyl-sn-glycerols differing in the acyl chain length, which varied from C4 to C18, were examined for their in vitro anti-tumor promoting effects on Epstein-Barr virus early antigen (EBV-BA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Among the… CONTINUE READING