Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells.

@article{Ogasawara2001InhibitoryEO,
  title={Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells.},
  author={Masaru Ogasawara and Takuma Matsubara and Hideyo Suzuki},
  journal={Biological & pharmaceutical bulletin},
  year={2001},
  volume={24 8},
  pages={917-20}
}
We have previously reported that evodiamine had a marked inhibitory activity on tumor cell migration in vitro. To extend our study, the effects of evodiamine on invasion, growth, and metastatic development of colon 26-L5 cells were examined here. Evodiamine inhibited the invasion of tumor cells into Matrigel in a concentration-dependent manner, and achieved… CONTINUE READING