Inhibitory effects of dioscorea polysaccharide on TNF-α-induced insulin resistance in mouse FL83B cells.

@article{Lee2011InhibitoryEO,
  title={Inhibitory effects of dioscorea polysaccharide on TNF-α-induced insulin resistance in mouse FL83B cells.},
  author={Bao-Hong Lee and Wei-Hsuan Hsu and Tzu-Ming Pan},
  journal={Journal of agricultural and food chemistry},
  year={2011},
  volume={59 10},
  pages={5279-85}
}
Dioscorea is a traditional medicinal food in Asia. This study investigated the anti-insulin resistance of dioscorea polysaccharide (DPS) in inflammatory factor (tumor necrosis factor-α; TNF-α) induced mouse normal liver FL83B cells. Insulin resistance was induced by treating cells with TNF-α (20 ng/mL) for 5 h; subsequently, the medium was replaced with insulin and DPS for 60 min of incubation (model 1; alleviating group). In addition, cells were cotreated with TNF-α and DPS for 5 h in model 2… CONTINUE READING

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