• Corpus ID: 22696600

Inhibitory effects of different lactobacilli on Candida albicans hyphal formation and biofilm development.

  title={Inhibitory effects of different lactobacilli on Candida albicans hyphal formation and biofilm development.},
  author={Carlotta Francesca Orsi and Carla Sabia and Andrea Ardizzoni and Bruna Colombari and Rachele Giovanna Neglia and Samuele Peppoloni and Giulia Morace and Elisabetta Blasi},
  journal={Journal of biological regulators and homeostatic agents},
  volume={28 4},
  • C. Orsi, C. Sabia, E. Blasi
  • Published 1 October 2014
  • Biology, Medicine
  • Journal of biological regulators and homeostatic agents
The aim of this study was to investigate the effects of different species of Lactobacilli on hyphal formation and biofilm development by the opportunistic fungal pathogen Candida albicans. We employed 4 different Lactobacillus species, namely L. rhamnosus, L. acidophilus, L. plantarum and L. reuteri, and 2 C. albicans strains, the reference DAY286 and its isogenic hwp1/hwp1 mutant, the FJS24 strain. As assessed by morphological analysis and quantitative colorimetric assays, Lactobacillus crude… 
Lactobacillus iners Cell-Free Supernatant Enhances Biofilm Formation and Hyphal/Pseudohyphal Growth by Candida albicans Vaginal Isolates
It is suggested that L. iners contributes to the pathogenesis of VVC and the complexity of the interaction between C. albicans and vaginal lactobacilli could prove essential for the development of new strategies for treating VVC.
Antifungal activity of clinical Lactobacillus strains against Candida albicans biofilms: identification of potential probiotic candidates to prevent oral candidiasis
The hindrance of biofilm development was characterized by the downregulated expression of C. albicans biofilm-specific genes (ALS3, HWP1, EFG1 and CPH1).
Antimicrobial Compounds Produced by Vaginal Lactobacillus crispatus Are Able to Strongly Inhibit Candida albicans Growth, Hyphal Formation and Regulate Virulence-related Gene Expressions
The novel findings suggest that L. crispatus, a dominant Lactobacillus species associated with a healthy vagina, could strongly inhibit C. albicans growth and hyphal formation and might repress the expression of hyphae-specific genes in a NRG1-dependent manner.
Probiotic lactobacilli inhibit early stages of Candida albicans biofilm development by reducing their growth, cell adhesion, and filamentation
The data elucidate the inhibitory mechanisms that define the probiotic candicidal activity of lactobacilli, thus supporting their utility as an adjunctive therapeutic mode against mucosal candidal infections.
Candida tropicalis affects the virulence profile of Candida albicans: an in vitro and in vivo study
Evaluated the interaction between species of the genus Candida in the biofilm formation, filamentation, gene expression and virulence in Galleria mellonella found C. tropicalis colonization was associated with a decrease in the growth of C. albicans, suggesting an antagonistic relation between these two species.
Action mechanisms of probiotics on Candida spp. and candidiasis prevention: an update
The purpose of this review was to gather different studies focused on the action mechanism of probiotic strains on Candida sp.
Lactobacillus casei reduces the extracellular matrix components of fluconazole-susceptible Candida albicans biofilms
Understanding of how the implementation of probiotics influences the growth of C. albicans biofilms is allowed and helps with the development of novel approaches to control these bioFilms.
Lactobacillus rhamnosus inhibits Candida albicans virulence factors in vitro and modulates immune system in Galleria mellonella
The aim of this study was to evaluate the potential anti‐Candida effects of Lactobacillus rhamnosus ATCC 9595 on Candida albicans ATCC 18804 using in vitro and in vivo models.