Inhibitory effects of carbamazepine on clonidine-induced aggressive behavior in mice.

@article{Fujiwara1988InhibitoryEO,
  title={Inhibitory effects of carbamazepine on clonidine-induced aggressive behavior in mice.},
  author={Yumi Fujiwara and Tadanao Takeda and Y. Kazahaya and Saburo Otsuki and Reuven Sandyk},
  journal={The International journal of neuroscience},
  year={1988},
  volume={42 1-2},
  pages={77-84}
}
A behavioral study was made of the effect of carbamazepine (CBZ) on aggressive behavior evoked by high dose of clonidine in mice. This aggressive behavior has been reported to involve blockade of central adenosine receptors with which CBZ has been suggested to interact. After a single injection of clonidine (50 mg/kg i.p.), aggressive responses such as attacking and biting began within 5-10 min, were most marked at 20 min and usually ceased within 60 min. This behavior was attenuated by CBZ (45… CONTINUE READING