Inhibitory effects of baicalein on the influenza virus in vivo is determined by baicalin in the serum.

@article{Xu2010InhibitoryEO,
  title={Inhibitory effects of baicalein on the influenza virus in vivo is determined by baicalin in the serum.},
  author={Ge Toby Xu and Jie Dou and Lei Zhang and Qinglong Guo and Changlin Zhou},
  journal={Biological & pharmaceutical bulletin},
  year={2010},
  volume={33 2},
  pages={238-43}
}
Baicalein, an extract from Scutellaria baicalensis, was evaluated for its ability to inhibit the influenza virus in vivo. Oral administration of baicalein to BALB/c mice infected with the influenza A/FM1/1/47(H1N1) virus showed significant effects in preventing death, increasing the mean time to death, inhibiting lung consolidation, and reducing the lung virus titer in a dose-dependent manner. These effects are believed to be due to baicalin, the metabolite of baicalein in the serum. At a… CONTINUE READING