Inhibitory effects of antithrombin III on interactions between blood cells and endothelial cells during retinal ischemia-reperfusion injury.

@article{Nishijima2003InhibitoryEO,
  title={Inhibitory effects of antithrombin III on interactions between blood cells and endothelial cells during retinal ischemia-reperfusion injury.},
  author={Kazuaki Nishijima and Junichi Kiryu and Akitaka Tsujikawa and Megumi Honjo and Atsushi Nonaka and Kenji Yamashiro and Hiroshi Kamizuru and Yoshiaki Ieki and Hidenobu Tanihara and Y. Hasegawa Honda and Yuichiro Ogura},
  journal={Investigative ophthalmology & visual science},
  year={2003},
  volume={44 1},
  pages={332-41}
}
PURPOSE Infiltrating leukocytes have long been widely thought to be key mediators of ischemia-reperfusion injury. Recently, however, evidence suggests that platelets accumulating in postischemic tissues also contribute to ischemia-reperfusion injury because of their inflammatory properties and promotion of formation of thrombi. This study was designed to evaluate quantitatively the inhibitory effects of antithrombin (AT)-III on the interactions between blood cells and retinal endothelial cells… CONTINUE READING

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