Inhibitory effects of a traditional Chinese herbal formula TBL-II on type II collagen-induced arthritis in mice.

@article{Shen2011InhibitoryEO,
  title={Inhibitory effects of a traditional Chinese herbal formula TBL-II on type II collagen-induced arthritis in mice.},
  author={Xiaoyan Shen and Cuixian Li and Huifang Zhao and Songhua Li and Jifan Chen and Yuta Kobayashi and Weixing Shen},
  journal={Journal of ethnopharmacology},
  year={2011},
  volume={134 2},
  pages={399-405}
}
AIM OF THE STUDY TBL-II is the water extract of an anti-arthritic Chinese herbal formula Tongbiling (TBL), which has been used to treat rheumatoid arthritis (RA) for many years. We herein aimed to confirm its anti-arthritic effect and explore the potential mechanism of action on collagen-induced arthritis (CIA) in mice. MATERIALS AND METHODS Four weeks after the first collagen immunization, mice were treated with TBL-II orally at a lower dose of 100mg/kg/d and higher dose of 300 mg/kg/d for 2… CONTINUE READING