Inhibitory effects of a manganese superoxide dismutase isolated from garlic (Allium sativum L.) on in vitro tumoral cell growth.

@article{Sfaxi2009InhibitoryEO,
  title={Inhibitory effects of a manganese superoxide dismutase isolated from garlic (Allium sativum L.) on in vitro tumoral cell growth.},
  author={Imen Hadji Sfaxi and Daniela Ferraro and Elena Fasano and Giovambattista Pani and Ferid Limam and Mohamed N{\'e}jib Marzouki},
  journal={Biotechnology progress},
  year={2009},
  volume={25 1},
  pages={257-64}
}
Reactive oxygen species are implicated in cancer development and antioxidants in general and superoxide dismutases and superoxide dismutase mimetic in particular, and they inhibit malignant transformation. We examinated the effects of an isolated manganese superoxide dismutase from a medicinal plant Allium sativum. The protein was prepared by a serial of chromatographic techniques: gel filtration and diethylaminoethyl ions exchanger. The enzyme has a specific activity equal to 55 U/mg. Two… CONTINUE READING