Corpus ID: 10370879

Inhibitory effect of suberogorgin on acetylcholinesterase.

@article{Peng1996InhibitoryEO,
  title={Inhibitory effect of suberogorgin on acetylcholinesterase.},
  author={W. Peng and S. Xu and X. Peng},
  journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  year={1996},
  volume={17 4},
  pages={
          369-72
        }
}
  • W. Peng, S. Xu, X. Peng
  • Published 1996
  • Biology, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica Sinica
AIM To study the selection, reversibility, and kinetics of suberogorgin (Sub) on acetylcholinesterase (AChE). METHODS The human plasma was used as butyrylcholinesterase (BuChE). The activity of ChE was determined with colorimetry. RESULTS Sub obviously inhibited the AChE in vitro with pl50 4.03, 4.92, 3.82, and 4.67 in RBC membranes (of rat and human) and tissue extracts (of rat brain and earthworm dorsal muscle), respectively. No inhibition on BuChE was observed. The inhibition of Sub on… Expand
Comparative neurotoxicity of two energetic compounds, hexanitrohexaazaisowurtzitane and hexahydro-1,3,5-trinitro-1,3,5-triazine, in the earthworm Eisenia fetida.
TLDR
The CL-20 is more potent than RDX, which is consistent with previous studies on lethality, growth, and reproduction endpoints in soil oligochaetes, and indicates that the neurotoxicity is reversible even after 6-d exposure. Expand
Natural products inhibitors of the enzyme acetylcholinesterase
TLDR
The present work reviews the literature on plants and plant-derived compounds inhibitors of enzyme acetylcholinesterase and refers to 309 plant extracts and 260 compounds isolated from plants, which are classified in appropriate chemical groups and model tested, and cites their activity. Expand