Corpus ID: 10370879

Inhibitory effect of suberogorgin on acetylcholinesterase.

  title={Inhibitory effect of suberogorgin on acetylcholinesterase.},
  author={W. Peng and S. Xu and X. Peng},
  journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  volume={17 4},
  • W. Peng, S. Xu, X. Peng
  • Published 1996
  • Biology, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica Sinica
AIM To study the selection, reversibility, and kinetics of suberogorgin (Sub) on acetylcholinesterase (AChE). METHODS The human plasma was used as butyrylcholinesterase (BuChE). The activity of ChE was determined with colorimetry. RESULTS Sub obviously inhibited the AChE in vitro with pl50 4.03, 4.92, 3.82, and 4.67 in RBC membranes (of rat and human) and tissue extracts (of rat brain and earthworm dorsal muscle), respectively. No inhibition on BuChE was observed. The inhibition of Sub on… Expand
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