Inhibitory effect of quercetin on rat trachea contractility in vitro.

  title={Inhibitory effect of quercetin on rat trachea contractility in vitro.},
  author={Raffaele Capasso and Gabriella Aviello and Barbara Romano and Giuseppina Atorino and Ester Pagano and Francesca Borrelli},
  journal={The Journal of pharmacy and pharmacology},
  volume={61 1},
OBJECTIVES The effect of quercetin, a naturally occurring flavonoid traditionally used to treat airway diseases such as bronchial asthma, on the contractile response elicited by electrical field stimulation or carbachol in rat isolated trachea was investigated. METHODS Isolated tracheal tissue was subjected to contractions by an electrical field stimulation of 5 Hz for 30 s, 400 mA, and the responses in the presence of cumulative concentrations of quercetin (10(-6)-3x10(-4) M) were observed… 

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