Inhibitory effect of phloretin and biochanin A on IgE-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells.

@article{Chung2013InhibitoryEO,
  title={Inhibitory effect of phloretin and biochanin A on IgE-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells.},
  author={Mi Ja Chung and Jae Kyung Sohng and Doo Jin Choi and Yong Il Park},
  journal={Life sciences},
  year={2013},
  volume={93 9-11},
  pages={
          401-8
        }
}
AIMS Anti-allergic effects and action mechanism of phloretin (Phl) and biochanin A (BioA) on the IgE-antigen complex-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells were investigated. MAIN METHODS Cell viability, formation of reactive oxygen species (ROS), DPPH radical-scavenging activity, β-hexosaminidase release, production of interleukin (IL)-4, IL-13, and tumor necrosis factor-alpha (TNF-α) and phosphorylation of Akt and mitogen-activated protein kinase (MAPK) were… CONTINUE READING
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